Publications & Patents

The written record.

Three peer-reviewed publications, and one European patent application as co-inventor. * denotes shared first authorship.

Patent

New compounds and use thereof

Bigot, K., Makhoul, P., El Hajj, H., Patinote, C., Larbouret, C., Deleuze-Masquefa, C., & Bonnet, P.-A.

Patent reference number BIO23267-T1 · filed 27 March 2025 · Inserm Transfert.

Co-inventor EAPB04303 European application

View on Inserm Transfert ↗

Publications

Showing 3 items

2025Biomolecules

The Novel Imiqualine EAPB02303 Is a Potent Drug for Treating Acute Myeloid Leukemia

Makhoul, P.*, Hleihel, R.*, Itani, S., Hamie, M., Pagniagua-Gayraud, S., Patinote, C., Richaud, M., Merhi, R. A., El-Sabban, M., Galas, S., Deleuze-Masquefa, C., Bonnet, P.-A., & El Hajj, H.

Biomolecules, 15(5), 741.

Shared first author DOI ↗

2024Int. J. Mol. Sci.

Uncovering the Molecular Pathways Implicated in the Anti-Cancer Activity of the Imidazoquinoxaline Derivative EAPB02303 Using a Caenorhabditis elegans Model

Makhoul, P., Galas, S., Paniagua-Gayraud, S., Deleuze-Masquefa, C., Hajj, H. E., Bonnet, P.-A., & Richaud, M.

International Journal of Molecular Sciences, 25(14), 7785.

First author DOI ↗

2022Front. Pharmacol.

HAS 1: A natural product from soil-isolated Streptomyces species with potent activity against cutaneous leishmaniasis caused by Leishmania tropica

Awada, B., Hamie, M., El Hajj, R., Derbaj, G., Najm, R., Makhoul, P., Ali, D. H., Abou Fayad, A. G., & El Hajj, H.

Frontiers in Pharmacology, 13, 1023114.

Co-author DOI ↗